Background：Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仕様
Synonyms：HBSC II,NAC2,Scn2a,SCN2A,SCN2A1,SCN2A2,Sodium channel protein brain II subunit alpha,Sodium channel protein type 2 subunit alpha,Sodium channel protein type II subunit alpha,Sodium channel protein,brain II subunit alpha,Voltage gated sodium channel subunit alpha Nav1.2,Voltage-gated sodium channel subunit alpha Nav1.2
Host：Rabbit
Reactivity：Human,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human SCN2A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
