Background:This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.
仕様
Synonyms:Na(+)/I(-) cotransporter,Na(+)/I(-) symporter,Na+/I- cotransporter,Na+/I-symporter,NIS,SC5A5,Slc5a5,sodium iodide symporter,Sodium-iodide symporter,Sodium/iodide cotransporter,Solute carrier family 5 (sodium iodide symporter) member 5,solute carrier family 5 (sodium/iodide cotransporter),member 5,Solute carrier family 5 member 5,TDH1
Host:Rabbit
Reactivity:Human
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human SLC5A5
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:Q92911
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction