Background:The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.
仕様
Synonyms:AAD10,ALL1 related gene,ALL1-related protein,ALR,CAGL114,Histone-lysine N-methyltransferase MLL2,KABUK1,Kabuki make up syndrome,Kabuki mental retardation syndrome,KMS,KMT2B,KMT2D,Lysine N methyltransferase 2D,Lysine N-methyltransferase 2B,MLL2,MLL2,MLL4,Myeloid/lymphoid or mixed lineage leukemia 2,Myeloid/lymphoid or mixed-lineage leukemia protein 2,TNRC21,Trinucleotide repeat containing 21
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human KMT2D
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3