Background：This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：BR,CD 49b,CD49 antigen like family member B,CD49 antigen-like family member B,CD49b,CD49b antigen,Collagen receptor,DX5,Glycoprotein Ia deficiency included,GP Ia,GP Ia deficiency,included,GPIa,HPA 5 included,HPA5 included,Human platelet alloantigen system 5,Integrin alpha 2,Integrin alpha II,Integrin alpha-2,Integrin,alpha 2 （CD49B alpha 2 subunit of VLA 2 receptor）,ITA2,ITGA2,Platelet alloantigen Br（a）,included,Platelet antigen Br,Platelet glycoprotein GPIa,Platelet glycoprotein Ia,Platelet glycoprotein Ia/IIa,Platelet membrane glycoprotein Ia,Platelet receptor for collagen,deficiency of,included,Very late activation protein 2 receptor alpha 2 subunit,VLA 2 alpha chain,VLA 2,VLA 2 subunit alpha,VLA-2 subunit alpha,VLA2,VLA2 receptor alpha 2 subunit,VLAA2
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human ITGA2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：25-1：100
Swissprot：P17301
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
