Background：The protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.
仕様
Synonyms：69 kDa peroxisomal ABC transporter,ABC 41,ABC41,ABCD 4,ABCD4,ABCD4,ATP binding cassette sub family D （ALD） member 4,ATP binding cassette sub family D member 4,ATP-binding cassette sub-family D member 4,EST352188,MAHCJ,MGC105956,P70R,P79R,Peroxisomal membrane protein 1 like,Peroxisomal membrane protein 1-like,Peroxisomal membrane protein 69,PMP 69,PMP69,PMP70-related protein,PXMP 1L,PXMP1 L,PXMP1-L,PXMP1L
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.1mg/mL
Immunogen：Synthetic peptide of human ABCD4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
