Background：This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
仕様
Synonyms：NAD dependent deacetylase sirtuin 5,NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial,NAD dependent protein deacylase sirtuin 5 mitochondrial,NAD-dependent protein deacylase sirtuin-5,mitochondrial,Regulatory protein SIR2 homolog 5,Silent mating type information regulation 2 S.cerevisiae homolog 5,Sir2 like 5,SIR2-like protein 5,SIR2L5,SIR5,Sirt5,Sirtuin 5,Sirtuin type 5
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human SIRT5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q9NXA8
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism
