Background：Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
仕様
Synonyms：CF2R,Coagulation factor II （thrombin） receptor,Coagulation factor II receptor,F2R,HTR,PAR 1,PAR-1,PAR1,PAR1,Protease activated receptor 1,Proteinase activated receptor 1,Proteinase-activated receptor 1,Thrombin receptor,TR
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human F2R
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P25116
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Signal transduction
