Background：GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol（GPI）-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.
仕様
Synonyms：GDNF family receptor alpha 3,GDNF family receptor alpha-3,GDNF receptor alpha-3,GDNFR-alpha-3,GDNFR3,GFR-alpha-3,GFRA3,GFRA3,Glial cell line derived neurotrophic factor receptor alpha 3,GPI linked receptor,OTTHUMP00000159486,OTTHUMP00000224020
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：1mg/mL
Immunogen：Synthetic peptide of human GFRA3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
