Background：This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：CSNB1C,Long transient receptor potential channel 1,LTrpC1,Melastatin 1,Melastatin-1,MLSN1,Transient receptor potential cation channel subfamily M member 1,Transient receptor potential cation channel,subfamily M,member 1,Transient receptor potential melastatin family,TRPM1,TRPM1 protein,TRPM1,Weakly similar to F54D1.5 [C.elegans]
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human TRPM1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
