Background：This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding （G） proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：Ednra,EDNRA,Endothelin 1 receptor precursor,Endothelin 1 specific receptor,Endothelin A receptor,Endothelin ET A receptor,Endothelin receptor ET1 specific type,Endothelin receptor subtype A,Endothelin receptor type A,Endothelin-1 receptor,ET A,ET-A,ETA,ETA R,ETA-R,ETAR,ETRA,G protein coupled receptor,hET AR,hET-AR,MFDA
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human EDNRA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：P25101
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
