Background：This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium（2+）-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain （in some isoforms）, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D （gD） of herpes simplex viruses 1 and 2 （HSV-1, HSV-2）, and pseudorabies virus （PRV） and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome （CLPED1） as well as non-syndromic cleft lip with or without cleft palate （CL/P）. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
仕様
Synonyms：CD111,CD111 antigen,CLPED1,ectodermal dysplasia 4 （Margarita Island type）,ED4,Herpes virus entry mediator C,Herpesvirus entry mediator C,Herpesvirus Ig like receptor,Herpesvirus Ig-like receptor,HIgR,HveC,MGC142031,Nectin 1,Nectin-1,OFC7,OROFACIAL CLEFT 7,OTTHUMP00000232093,OTTHUMP00000232094,OTTHUMP00000232095,Poliovirus receptor related protein 1,poliovirus receptor-like 1,Poliovirus receptor-related protein 1,PRR,PRR1,PVRL 1,PVRL1,PVRL1,PVRR,PVRR1,SK-12
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human PVRL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
