Background:This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, whicHuman, Mouseay include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription.
仕様
Synonyms:CCN T1,CCNT,CCNT 1,Ccnt1,CCNT1,CDK9 associated C type protein,Cyc T1,Cyclin C related protein,Cyclin T,cyclin T1,Cyclin T1b,Cyclin-T,Cyclin-T1,CYCT 1,CycT1,HIVE1,Human immunodeficiency virus 1 expression,Human immunodeficiency virus type 1 (HIV 1) expression (elevated) 1,pTEFb subunit,Subunit of positive elongation transcription factor b
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human CCNT1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:O60563
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Microbiology