Background:The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
仕様
Synonyms:CK 16,CK-16,CK16,Cytokeratin-16,Cytokeratin16,FNEPPK,Focal non epidermolytic palmoplantar keratoderma,K 16,K16,K1C16,K1CP,Keratin 1 type I,Keratin 16,Keratin,Keratin type I cytoskeletal 16,Keratin-16,Keratin16,KRT 16,Krt16,KRT16A,NEPPK,PC1,type I cytoskeletal 16
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human KRT16
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3