Background:This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.
仕様
Synonyms:CBX 1,CBX,Cbx1,CBX1,Chromobox 1,Chromobox homolog 1 (HP1 beta homolog Drosophila ),chromobox homolog 1,Chromobox protein homolog 1,Drosophila HP1 beta,Heterochromatin protein 1 beta,Heterochromatin protein 1 homolog beta,Heterochromatin protein p25,heterochromatin protein p25 beta,HP1 beta,HP1 beta homolog,HP1 beta homolog Drosophila,HP1,Drosophila. homolog of,beta,HP1beta,HP1Hs beta,HP1Hsbeta,Human heterochromatin protein p25 mRNA complete cds,M31,MOD 1,MOD1,Modifier 1 protein,p25beta
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human CBX1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:15-1:50
Swissprot:P83916
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling