Background：This gene encodes a member of the basic helix-loop-helix （BHLH） family of transcription factors. The protein activates transcription by binding to the E box （5'-CANNTG-3'）. Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome （CCHS） phenotype in rare cases.
仕様
Synonyms：Achaete scute complex homolog 1,Achaete scute complex homolog like 1,Achaete scute complex homologue 1,Achaete scute complex homologue like 1,Achaete scute complex like 1,Achaete scute family bHLH transcription factor 1,Achaete scute protein,Achaete-scute homolog 1,Ascl 1,ascl1,ASCL1,Ash 1,ASH-1,Ash1,bHLHa46,Class A basic helix-loop-helix protein 46,Hash 1,HASH1,Mammalian achaete scute homolog 1,Mammalian achaete scute homologue 1,Mash 1,Mash1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.1mg/mL
Immunogen：Synthetic peptide of human ASCL1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P50553
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Neuroscience
