Background：The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
仕様
Synonyms：Activin beta-A chain,EDF,Erythroid differentiation factor,Erythroid differentiation protein,Follicle stimulating hormone releasing protein,FRP,FSH releasing protein,INHBA,INHBA,Inhibin beta A chain,Inhibin beta A subunit,Inhibin,beta 1,Inhibin,beta A （activin A,activin AB alpha polypeptide）
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human INHBA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
