Background:The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
仕様
Synonyms:ADH water channel,AQP 2,AQP CD,AQP-2,AQP-CD,AQP2,AQP2,AQPCD,Aquaporin 2 collecting duct,Aquaporin CD,Aquaporin-2,Aquaporin-CD,Aquaporin2,Aquaporine 2,Collecting duct water channel protein,MGC34501,Water channel aquaporin 2,Water channel protein for renal collecting duct,WCH CD,WCH-CD,WCHCD
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human AQP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:P41181
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction