Background：This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仕様
Synonyms：Aplysia RAS-related homolog 9,ARH 9,ARH9,ARHC,H9,MGC1448,MGC61427,Oncogene RHO H9,Ras homolog gene family member C,RAS related homolog 9,RHO C,Rho cDNA clone 9,Rho related GTP binding protein RhoC,Rho-related GTP-binding protein RhoC,rhoC,RhoC GTPase,RHOC,RHOH 9,RHOH9,Small GTP binding protein RhoC
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human RHOC
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
