Background：The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated witHuman, Mousealignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：BAF47,BRG1-associated factor 47,hSNF5,INI1,Integrase interactor 1 protein,Malignant rhabdoid tumor suppressor,RDT,RTPS1,Sfh1p,SMARCB1,SNF5 homolog,SNF5,SNF5L1,Snr1,Sucrose nonfermenting yeast homolog like 1,SWI/SNF complex component SNF5,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,SWI10,Transcription factor TYE4,Transcription regulatory protein SNF5,TYE4
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human SMARCB1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：30-1：150
Swissprot：Q12824
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
