Background：Ras-related GTP-binding protein Ais aproteinthat in humans is encoded by theRRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
仕様
Synonyms：Adenovirus E3 14.7 kDa-interacting protein 1,FIP-1,Rag A,RagA,Ras-related GTP-binding protein A,RRAGA,RRAGA
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human RRAGA
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：Q7L523
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Microbiology, Signal transduction
