Background:The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
仕様
Synonyms:95 kDa retinoblastoma associated protein,95 kDa retinoblastoma protein binding protein,95 kDa retinoblastoma-associated protein,BRE 1B,BRE1 B,BRE1 E3 ubiquitin ligase homolog B,BRE1-B,BRE1B,BRE1B,DKFZp686K191,E3 ubiquitin protein ligase BRE1B,E3 ubiquitin-protein ligase BRE1B,KIAA0661,MGC13051,Rb associated protein,RBP 95,RBP95,RING finger protein 40,Ring finger protein 40 E3 ubiquitin protein ligase,RNF 40,Rnf40,STARING
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human RNF40
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3