Background：This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
仕様
Synonyms：Hematopoietic cell protein tyrosine phosphatase 70Z PEP,Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP,Lymphoid phosphatase,Lymphoid specific protein tyrosine phosphatase,lymphoid-specific,inducible human protein tyrosine phosphatase,Lyp 1,Lyp 2,LyP,Lyp1,Lyp2,LyPTP,OTTHUMP00000013720,OTTHUMP00000013721,OTTHUMP00000233450,OTTHUMP00000233451,PEP,PEST-domain phosphatase,Protein tyrosine phosphatase non receptor type 22 （lymphoid）,Protein tyrosine phosphatase non receptor type 22,Protein tyrosine phosphatase non receptor type 8,Protein tyrosine phosphatase non receptor type 8,formerly,PTN22,PTPN 22,PTPN 8,Ptpn22,PTPN8,PTPN8,formerly,Tyrosine-protein phosphatase non-receptor type 22
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human PTPN22
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
