Background：This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 （mTORC2）, and it regulates platelet-derived growth factor （PDGF） receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms.
仕様
Synonyms：Arhgap8,AU043908,C030017C09Rik,C78947,FLJ20185,FLJ20185k,MGC109513,MGC32512,PP610,Proline rich 5 （renal）,Proline-rich protein 5,Protein observed with Rictor-1,Protor-1,PROTOR1,PRR5,PRR5,PTOR1,Rho GTPase activating protein 8,RP1-181C9.3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.1mg/mL
Immunogen：Recombinant protein of human PRR5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：P85299
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction
