Background:This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
仕様
Synonyms:AI467657,lu,PLZF,Promyelocytic leukemia zinc finger protein,ZBT16,ZBTB16,Zfp145,Zinc finger and BTB domain containing 16,zinc finger and BTB domain containing protein 16,Zinc finger and BTB domain-containing protein 16,Zinc finger protein 145 (Kruppel like expressed in promyelocytic leukemia),Zinc finger protein 145,Zinc finger protein PLZF,Znf145
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human ZBTB16
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000
Swissprot:Q05516
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells