Background:This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms:Amplified in osteosarcoma 9,amplified in osteosarcoma,ERLEC2,OS-9,Os9,OS9,Osteosarcoma amplified 9 endoplasmic reticulum lectin,Protein OS-9
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human OS9
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:25-1:100
Swissprot:Q13438
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism