Background:This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Early response protein NAK1,GFRP 1,GFRP,GFRP1,Growth factor inducible nuclear protein N10,Growth Factor Inducible Nuclear Protein NP10,Growth Factor Response Protein 1,Hbr1,HMR,Hormone Receptor,MGC9485,N10,N10 nuclear protein,NAK 1,NAK1,Nerve growth factor IB nuclear receptor variant 1,NGFIB,NP 10,NP10,NR4A1,NR4A1,Nuclear hormone receptor NUR/77,Nuclear Hormone Receptor TR3,Nuclear receptor subfamily 4 group A member 1,NUR77,NUR77,mouse,homolog of,Orphan nuclear receptor HMR,Orphan nuclear receptor NR4A1,Orphan nuclear receptor TR3,Orphan receptor tr3,Receptor NGFIB,ST 59,ST-59,ST59,Steroid receptor TR3,Testicular receptor 3,TR 3,TR3,TR3 orphan receptor
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human NR4A1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P22736
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling