Background:This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
仕様
Synonyms:BC059730,CI 13kA,CI 13kD A,CI-13kD-A,CI13KDA,Complex I 13kD A,Complex I 13kDa subunit A,Complex I mitochondrial respiratory chain 13 kD subunit,Complex I-13kD-A,IP13,MGC107676,NADH dehydrogenase (ubiquinone) Fe-S protein 6,13kDa (NADH coenzyme Q reductase),NADH dehydrogenase [ubiquinone] iron sulfur protein 6,mitochondrial,NADH dehydrogenase [ubiquinone] iron-sulfur protein 6,mitochondrial,NADH ubiquinone oxidoreductase 13 kDa A subunit,NADH-ubiquinone oxidoreductase 13 kDa-A subunit,NADH:ubiquinone oxidoreductase NDUFS6 subunit,NADH:ubiquinone oxidoreductase subunit S6,Ndufs6,NDUS6
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human NDUFS6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:O75380
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction, Tags & Cell Markers