Background:This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs).
仕様
Synonyms:CD204,CD204 antigen,CD24,Macrophage acetylated LDL receptor I and II,Macrophage scavenger receptor 1,Macrophage scavenger receptor type III,Macrophage scavenger receptor types I and II,Msr 1,MSR1,MSRE,phSR1,phSR2,SCARA 1,SCARA1,Scavenger receptor class A member 1,Scavenger receptor class A,member 1,Scavenger receptor type A,Scvr,SR A,SRA
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human MSR1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:P21757
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Immunology