Background：This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase （ERK） pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 （EGLN3, also known as PHD3） and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：MAPK organizer 1,MGC4238,Mitogen activated protein kinase organizer 1＞,Mitogen-activated protein kinase organizer 1,MORG 1,WD repeat domain-containing protein 83,wdr83,WDR83
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human WDR83
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：100-1：300
Swissprot：Q9BRX9
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Signal transduction
