Background：Lysophosphatidic acid phosphatase type 6 （ACP6）, also designated acid phosphatase-like protein 1 （ACPL1） or lysophosphatidic acid phosphatase （LPAP）, is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8％ of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
仕様
Synonyms：Acid phosphatase 6,Acid phosphatase 6,lysophosphatidic,Acid phosphatase like 1,Acid phosphatase like protein 1,Acid phosphatase-like protein 1,ACP6,ACPL1,LPAP,Lysophosphatidic acid phosphatase 6,Lysophosphatidic acid phosphatase type 6,Lysophosphatidic acid phosphatase type 6 precursor,lysophosphatidic,PACPL1,PPA6
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human ACP6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
