Background：The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B （NF-kappaB）. The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
仕様
Synonyms：BCUR1,Breast cancer up regulated 1,Breast cancer upregulated 1,Gm366,Ldoc1,LDOC1,Leucine zipper down regulated in cancer 1,Leucine zipper protein down regulated in cancer cells,Leucine zipper protein down regulated in cancer cells,Leucine zipper protein down-regulated in cancer cells,Mar7,Mart7,Protein LDOC1,RGD1565644
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human LDOC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O95751
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
