Background：Intelectin-1also known as theintestinal lactoferrin receptoris aproteinthat in humans is encoded by theITLN1gene.Intelectin-1 functions both as a receptor for bacterialarabinogalactansand forlactoferrin. Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.
