Background:This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.
仕様
Synonyms:IFI1,Iigp3,Iipg3,Immunity related GTPase family M protein 1,Immunity related GTPase family,M,Immunity-related GTPase family M protein 1,Immunity-related GTPase family M protein,Interferon inducible protein 1,Interferon-inducible protein 1,Irgm,IRGM,IRGM1,LPS-stimulated RAW 264.7 macrophage protein 47 homolog,LRG 47,LRG-47,LRG-47-like protein,LRG47,MGC149263,MGC149264
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human IRGM
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:50-1:200
Swissprot:A1A4Y4
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Immunology, Signal transduction, Stem cells