Background：The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins （SREBPs） by binding to SREBP cleavage-activating protein （SCAP）, and thus prevent SCAP from escorting SREBPs to the Golgi.
仕様
Synonyms：Hypothetical protein INSIG2,INSIG 2,INSIG 2 membrane protein,INSIG2 membrane protein,Insulin induced gene 2,Insulin induced gene 2 protein,Insulin induced protein 2,MGC26273
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human INSIG2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q9Y5U4
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
