Background:The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms:HSDB,HSD3B,SDR11E2
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human HSD3B2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:P26439
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction