Background：The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency （DBPD）. An apparent pseudogene of this gene is present on chromosome 8.
仕様
Synonyms：12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase,17 beta HSD 4,17 beta HSD IV,17 beta hydroxysteroid dehydrogenase 4,17-beta-HSD 4,17-beta-hydroxysteroid dehydrogenase 4,17beta estradiol dehydrogenase type IV,3 alpha 7 alpha12 alpha trihydroxy 5 beta cholest 24 enoyl CoA hydratase,3-alpha,7-alpha,Beta hydroxyacyl dehydrogenase,Beta keto reductase,D 3 hydroxyacyl CoA dehydratase,D bifunctional protein,D bifunctional protein peroxisomal,D-3-hydroxyacyl CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein,D-bifunctional protein,D-bifunctional protein,peroxisomal,DBP,DBP,peroxisomal,DHB4,EDH17B4,Enoyl-CoA hydratase 2,Hsd17b4,MFE 2,MFE-2,MPF-2,Multifunctional protein 2,Peroxisomal multifunctional enzyme type 2,Peroxisomal multifunctional protein 2,PRLTS1,SDR8C1,Short chain dehydrogenase/reductase family 8C member 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Recombinant protein of human HSD17B4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P51659
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
