Background：The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：Cas like docking,Cas scaffolding protein family member 2,CAS-L,CAS2,CasL,CASL,CASS2,Crk associated substrate related,Crk associated substrate related protein,CRK-associated substrate-related protein,dJ49G10.2 （Enhancer of Filamentation 1 （HEF1））,dJ49G10.2,dJ761I2.1 （enhancer of filamentation （HEF1））,dJ761I2.1,Enhancer of filamentation 1,Enhancer of filamentation 1 p55,HEF 1,HEF1,NEDD-9,Nedd9,Neural precursor cell expressed developmentally down-regulated protein 9,P105,Renal carcinoma antigen NY-REN-12
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human NEDD9
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q14511
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction
