Background:This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
仕様
Synonyms:2700054G14Rik,AU022060,B16.6,CDA016,Cell death regulatory protein,Cell death regulatory protein GRIM-19,CGI-39,CGI39 protein,CI-B16.6,Complex I-B16.6,FLJ58045,FLJ59191,Gene associated with retinoic and IFN-induced mortality 19 protein,Gene associated with retinoic and interferon-induced mortality 19 protein,Gene associated with retinoic interferon induced mortality 19 protein,GRIM-19,NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,13,NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13,NADH ubiquinone oxidoreductase B16.6 subunit,NADH-ubiquinone oxidoreductase B16.6 subunit,NDUAD,NDUFA13,RGD1565358
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human NDUFA13
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:200
Swissprot:Q9P0J0
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism