Background:The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
仕様
Synonyms:bHLHb26,Cell growth inhibiting gene 8,class B basic helix loop helix protein 26,Class B basic helix-loop-helix protein 26,DNA binding protein inhibitor ID 2,DNA binding protein inhibitor ID2,DNA-binding protein inhibitor ID-2,GIG 8,GIG8,Helix loop helix protein ID2,ID2,ID2,ID2A,ID2H,Inhibitor of differentiation 2,Inhibitor of DNA binding 2,Inhibitor of DNA binding 2,dominant negative helix loop helix protein,MGC26389
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human ID2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q02363
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Stem cells