Background:This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
仕様
Synonyms:AlkB homolog 9,ALKBH9,Alpha-ketoglutarate-dependent dioxygenase FTO,AW743446,Fat mass and obesity-associated protein,FATSO,MOUSE,HOMOLOG OF,Fto,FTO,GDFD,KIAA1752,mKIAA1752,Protein fatso
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Recombinant protein of human FTO
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:100-1:300
Swissprot:Q9C0B1
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Neuroscience