Background：This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms：CD89,Fc alpha receptor,Fc fragment of IgA,receptor for,FCAR,FCAR,IgA Fc receptor,Immunoglobulin alpha Fc receptor
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Recombinant protein of human FCAR
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
