Background：Fc receptors specifically bind to the Fc region of immunoglobulins （Igs） to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM. May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream.
仕様
Synonyms：Faim3,FAIM3,Fas apoptotic inhibitory molecule 3,Fc fragment of IgM receptor,Fc mu receptor,FCMR,IgM Fc receptor,Immunoglobulin mu Fc receptor,Regulator of Fas induced apoptosis,Regulator of Fas-induced apoptosis Toso,TOSO
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human FAIM3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
