Background:The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
仕様
Synonyms:Villin 2 ezrin,CVIL,CVL,Cytovillin 2,Cytovillin,DKFZp762H157,Epididymis secretory protein Li 105,EZR,EZRI,Ezrin,FLJ26216,HEL S 105,MGC1584,p81,VIL 2,VIL2,Villin 2 (ezrin),Villin 2,Villin-2,Villin2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Recombinant protein of human EZR
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3