Background：This gene encodes a member of the estrogen receptor-related receptor （ESRR） family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor （ER） family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways.
仕様
Synonyms：DKFZp781L1617,ERR 3,ERR G2,ERR gamma 2,ERR gamma-2,ERR3,ERR3,ERRG 2,ERRG2,ERRgamma,ESRRG,Estrogen receptor related protein 3,Estrogen receptor-related protein 3,Estrogen-related receptor gamma,FLJ16023,KIAA0832,NR3B3,Nuclear receptor subfamily 3 group B member 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Recombinant protein of human ESRRG
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：P62508
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
