Background:Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
仕様
Synonyms:Beta protein 1,BP1,Distal less homeo box 7,Distal less homeo box 9,distal-less homeobox 4,DLX4,DLX4,DLX7,DLX8,DLX9,Homeobox protein DLX-4,Homeobox protein DLX-7,Homeobox protein DLX-8,Homeobox protein DLX4
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Recombinant protein of human DLX4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:1000-1:5000
Swissprot:Q92988
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling