Background：Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
仕様
Synonyms：ARVC 10,ARVC10,ARVD 10,ARVD10,Cadherin family member 5,CDHF 5,CDHF5,CMD1BB,Desmoglein 2,Desmoglein-2,Desmoglein2,DSG 2,DSG2,DSG2,HDGC,HDGC included,Human Desmoglein colon,MGC117034,MGC117036,MGC117037
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：1.5mg/mL
Immunogen：Recombinant protein of human DSG2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：100-1：300
Swissprot：Q14126
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Signal transduction
