Background：DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 （DEAD （Asp-Glu-Ala-Asp） box polypeptide 43）, also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis.
仕様
Synonyms：Cancer/testis antigen 13,CT13,DDX43,DDX43,DEAD box protein 43,DEAD box protein HAGE,HAGE,Helical antigen,Probable ATP dependent RNA helicase DDX43,Probable ATP-dependent RNA helicase DDX43
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Recombinant protein of human DDX43
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：50-1：200
Swissprot：Q9NXZ2
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
