Background:This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:DARPP 32,DARPP-32,Dopamine and cAMP regulated neuronal phosphoprotein 32,Dopamine and cAMP regulated neuronal phosphoprotein,Dopamine and cAMP regulated phosphoprotein,Dopamine and cAMP regulated phosphoprotein DARPP 32,Dopamine and cAMP regulated phosphoprotein DARPP32,Dopamine- and cAMP-regulated neuronal phosphoprotein,FLJ20940,IPPD,Neuronal phosphoprotein DARPP 32,PPP1R1B,PPR1B,Protein phosphatase 1 regulatory (inhibitor) subunit 1B,Protein phosphatase 1 regulatory inhibitor subunit 1B,Protein phosphatase 1 regulatory subunit 1B
Host:Rabbit
Reactivity:Human,Rat
Applications:IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Recombinant protein of human PPP1R1B
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q9UD71
Isotype:IgG
Research Areas:Cancer, Metabolism, Neuroscience, Signal transduction