Background:The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
仕様
Synonyms:Cyclophilin 3,cyclophilin D,Cyclophilin F,Cyp D,CyP M,CYP3,CypD,hCyP3,mitochondrial,Mitochondrial cyclophilin,Peptidyl prolyl cis trans isomerase,mitochondral,Peptidyl-prolyl cis-trans isomerase F,Peptidyl-prolyl cis-trans isomerase F,mitochondrial,Peptidylprolyl isomerase F (cyclophilin F),Peptidylprolyl isomerase F,PPIase,PPIase F,Ppif,PPIF,Rotamase,Rotamase F
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Recombinant protein of human PPIF
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:100-1:300
Swissprot:P30405
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Immunology, Signal transduction