Background:The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.
仕様
Synonyms:AA408962,AA553318,AI844835,Cphn 2,Cphn2,Cyclophilin B,Cyclophilin like protein,CyP 20b,CYP S1,CYP-S1,CYPB,EC 5.2.1.8,MGC14109,MGC2224,OI9,peptidyl prolyl cis trans isomerase B,Peptidyl prolyl cis trans isomerase B precursor,Peptidyl-prolyl cis-trans isomerase B,peptidylprolyl isomerase B (cyclophilin B),Peptidylprolyl isomerase B,PPIase,PPIase B,Ppib,PPIB,Rotamase,Rotamase B,S cyclophilin,S-cyclophilin,SCYLP
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Recombinant protein of human PPIB
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:100-1:300
Swissprot:P23284
Isotype:IgG
Research Areas:Cancer, Immunology, Signal transduction